Optimizing endothelial targeting by modulating the antibody density and particle concentration of anti-ICAM coated carriers
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چکیده
منابع مشابه
Optimizing endothelial targeting by modulating the antibody density and particle concentration of anti-ICAM coated carriers.
Targeting of drug carriers to cell adhesion molecules expressed on endothelial cells (ECs) may improve treatment of diseases involving the vascular endothelium. This is the case for carriers targeted to intercellular adhesion molecule 1 (ICAM-1), an endothelial surface protein overexpressed in many pathologies. In order to optimize our design of anti-ICAM carriers, we have explored in this stud...
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ژورنال
عنوان ژورنال: Journal of Controlled Release
سال: 2011
ISSN: 0168-3659
DOI: 10.1016/j.jconrel.2010.10.025